BioE 594
-- Design and Implementation of Computational Methods in Bioinformatics


Current Project Assignment
Proj1 : Yang & Zhengden, Lei & Arun (April 20)
Proj2 : Nihar & Harish, (April 20), Ying & Xiaolong , Jessica (April 22)
Proj3 : Eyad & Nitin, Satya, Mohanraj& Pavan (April 22)
Proj4 : Guanrao & Xiang, Marianela, Joe,john (April 27)
Proj5

Class Schedule
Please note that this is a tentative schedule, subject to change

No. date topic notes etc.
1 Jan 13 (Tu) Course Overview
Getting R and Matlab ready
R, Intr R,
Intro to genome biology, Basic lab techiques,
paper, homework assignmrnt 1
2 Jan 15 (Tr) Microarray technology, R slides, short movie
r-intro
3 Jan 20 (Tu) Review of satistics 1 slides
4 Jan 22 (Tr) Review of satistics 2 slides
homework assignment 2
5 Jan 27 (Tu) student's presentation papers [1],[2], [3]
6 Jan 29(Tr) Pre-processing: cDNA microarrays slides, lowess
papers [1], [2]
7 Feb 3 (Tu) Pre-processing: Affymetrix GeneChip arrays slides
papers [1], [2], [3]
8 Feb 5 (Tr) Pre-processing with Bioconductor slides, Bioconductor-Overview,
Bioconductor-URL
homework assignment 3
9 Feb 10 (Tu) Multiple testing slides
papers [1], [2], [3]
10 Feb 12 (Tr) Resampling and Bootstrap-1 slides
papers [1],[2], paper [3]
11 Feb 17 (Tu) Resampling and Bootstrap-2 slides
12 Feb 19 (Tr) student's presentation and
discussion about homework
13 Feb 24 (Tu) Genomic data-mining methods 1 slides
14 Feb 26 (Tr) Genomic data-mining methods 2 slides see above
homework assignment 4
15 March 2 (Tu) Genomic data-mining methods 3 slides
16 March 4 (Tr) Genomic data-mining methods 4 slides
papers [1], [2], [3]
17 March 9 (Tu) Genomic data-mining methods 5 slides (updated)
paper [1]
18 March 11 (Tr) Genomic data-mining methods 6
slides
paper [1]
19 March 16 (Tr) Genomic data-mining methods 8
slides
20 March 18 (Tu) Genomic data-mining methods 7
slides, tutorial by Bernhard Schölkopf,
(This tutorial is not included in exam, only for your reference)
final project
assignment see top of the page
21 March 23 (Tu) Spring break, No class
22 March 25 (Tr) Spring break, No class
23 March 30 (Tu) Genomic data-mining methods 9 slides (see above)
24 April 1 (Tu) Genomic data-mining methods 10 slides (see slides on Mar.18. slides updated after p44)
25 April 6 (Tu) infer genetic network -1 slides
homework assignment 5
individual presentation date posted , see top of the page
26 April 8 (Tr) infer genetic network -2 slides (see above)
27 April 13 (Tu) protein structure and function prediction
slides
28 April 15 (Tr) protein structure and function prediction-2 slides
29 April 20 (Tu) final project presentation
30 April 22 (Tr) final project presentation
31 April 27 (Tr) final project presentation
32 April 29 (Tu) Final Exam