Curriculum Vitae
I am going to work as a high-throughput computational analyst at Memorial Sloan-Kettering Cancer Center from October, 2007.
CURRENT RESEARCH INTERESTS
Data mining, text mining, statistical learning, and statistical analysis
Computational genome annotation
Genome-wide prediction of disease-relevant genes
EDUCATION
2003 - 2007 | University of Illinois at Chicago, |
| Bioinformatics, PhD |
1998 - 2001 | National Chromatographic Research & Analysis Center, |
| Dalian Institute of Chemical Physics, Chinese Academy of Sciences, |
| Analytical Chemistry, MS |
1994 - 1998 | College of Chemistry and Molecular Engineering, |
| Peking University, |
| Analytical Chemistry, BS |
TEACHING
Teaching Assistant "Introduction to Biostatistics" BIOE439 Spring 2007 for BiTmaP training program @ UIC
Teaching Assistant "Introduction to Biostatistics" BIOE439 Fall 2006 for BiTmaP training program @ UIC
Teaching Assistant "Introduction to Biostatistics" BIOE439 Spring 2006
WORK EXPERIENCE
2001 - 2003 | Keyou Software Company, China |
| Team Sub-leader / Team Leader |
Projects
Project 1: COSMOS: Toyota e-commerce system, Pro*C, Oracle
Project 2: Roller pole inspector: A quality control system for precision instruments based on edge detection, Visual C++
Project 3: Company management system, Java (struts framework), Oracle
Project 4: Sales management system, Visual Basic, SQL Server
HONORS
"Innovation Cup" Individual Computer Science Competition, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Rank 5th, 2000.
Privilege to enter Graduate Program at Chinese Academy of Sciences, waived of the qualification test, 1998.
University Student English Composition Competition, Beijing, Second Prize, 1996.
COMPUTER SKILL
Language: | c/c++ (MFC & STL),Perl, Java, VB(including VBA), R, SAS, etc.
|
Algorithm: | Genetic Algorithm, Simulated Annealing, Support Vector Machine, Neural Network, Wavelet Analysis, Clustering. |
Database: | Oracle(PL/SQL), SQL Server, mysql. |
WEB SERVER
Subnuclear Compartments Prediction System (Version 2.0)
My personal server based on JBOSS
PROFESSIONAL ACTIVITY
Peer Review for Journals:
Bioinformatics
FEBS Letters
Review for Conference:
IEEE EMBS 2006
BMES (Biomedical Engineering Society) membership
PUBLICATIONS [J-Journal, C-Conference, P-Poster, PT-Patent]
Journal papers
[J13] Zhengdeng Lei, Yang Dai
Assessing protein
similarity with Gene Ontology and its use in subnuclear localization
prediction;
BMC bioinformatics, 2006, 7:491[pdf]
[J12] Zhengdeng Lei, Yang Dai
An SVM-based system for predicting protein
subnuclear localizations;
BMC bioinformatics, 2005, 6:291 [pdf]
[J11] Zhengdeng Lei, Yang Dai
A class of new kernels based on a matrix of
high-scored pairs of k-peptides and its applications in prediction of protein
sub-cellular localization;
LNCS Transactions on Computational Systems
Biology II, Springer-Verlag, 2005, 3680, 48-58 [pdf]
[J10] Zhong Guo, Songyun Xu, Zhengdeng Lei, Hanfa Zou, Baochuan
Guo
Immobilized metal-ion chelating capillary microreactor for peptide
mapping analysis of proteins by matrix assisted laser desorption/ionization-time
of flight-mass spectrometry;
Electrophoresis 2003, 24, 3633-3639 [pdf]
[J9] Mingliang Ye, Hanfa Zou, Renan Wu, Hongjing Fu, Zhengdeng Lei
Modeling
and optimization for separation of ionic solutes in pressurized flow Capillary
electrochromatography;
J. Sep. Sci., 2002, 25, 416-426 [pdf]
[J8] Mingliang Ye, Hanfa Zou, Zhen Liu, Zhengdeng Lei, Renan Wu, Jianyi
Ni
Study of competitive binding of enantiomers to protein by affinity
capillary electrochromatography;
J. Pharm. Boimed. Anal., 2002, 27,
651-660 [pdf]
[J7] Mingliang Ye, Hanfa Zou, Zhengdeng Lei, Renan Wu, Zhen Liu, Jianyi
Ni
Enantiomer separation by strong anion-exchange capillary
electrochromatography with dynamically modified sulfated beta-cyclodextrin;
Electrophoresis 2001, 22, 518-525 [pdf]
[J6] Zhengdeng Lei, Mingliang Ye, Hanfa Zou, Renan Wu, Jianyi Ni
Separation
of Anionic Compounds by Strong Anion-Exchange Capillary
Electrochromatography;
Chinese J. Anal. Chem. 2001, 29:262-266 [pdf]
[J5] Renan Wu, Hanfa Zou, Mingliang Ye, Zhengdeng Lei, Jianyi Ni
Capillary
electrochromatography for separation of peptides driven with electrophoretic
mobility on monolithic column;
Anal. Chem., 2001, 73, 4918-4923 [pdf]
[J4] Mingliang Ye, Hanfa Zou, Zhengdeng Lei, Renan Wu, Jianyi
Ni
Hydrophilic interaction capillary electrochromatography for separation of
polar compounds;
LC&GC, 2001, 19, 1076-1079 [pdf]
[J3] Renan Wu, Hanfa Zou, Mingliang Ye, Zhengdeng Lei, Jianyi Ni
Separation
of basic, acidic and neutral compounds on CEC with uncharged monolithic
capillary column modified with anionic and cationic
surfactants;
Electrophoresis, 2001, 22, 544-551 [pdf]
[J2] Mingliang Ye, Hanfa Zou, Zhengdeng Lei, Renan Wu, Zhen Liu, Jianyi
Ni
Separation of acidic and neutral compounds by strong anion-exchange
capillary electrochromatography dynamically modified with sodium
dodecylsulfate;
Chromatographia 2001, 53, 425-430 [pdf]
[J1] Mingliang Ye, Hanfa Zou, Zhen Liu, Zhengdeng Lei, Jianyi Ni
Study on
the open tubular capillary affinity liquid chromatography;
J. Chromatogr.
Sci., 2000, 38, 517-520 [reprint]
Conference papers
[C2] Zhengdeng Lei, Yang Dai
A new kernel based on a matrix of high-scored
pairs of tri-peptides and its applications in prediction of protein sub-cellular
localization;
Proceedings of International Workshop on Bioinformatics
Research and Applications, 2005, 3515, 903-910 [pdf]
[C1] Zhengdeng Lei, Yang Dai
A novel approach for prediction of protein
subcellular localization from sequence using Fourier analysis and support vector
machines;
Proceedings of 4th ACM SIGKDD Workshop on Data Mining in
Bioinformatics, 2004, p11-17 [pdf]
Patent
[PT1] Zhengdeng Lei, Zhong Guo, Hanfa Zou, Qingchun Zhang, Liang
Kong
Construction and regeneration of an enzyme micro-reactor and its
application in protein identification;
China Patent (CN 01136860.8);
2001 [pdf]
Posters
[P3] Zhengdeng Lei and Yang Dai
Improve protein subnuclear localization prediction by incorporating Gene Ontology
Annual Fall Meeting of the Biomedical Engineering Society (BMES), Chicago, October 11-14, 2006
[P2] Zhengdeng Lei and Yang Dai
A new kernel based on a matrix of high-scored pairs of k-peptides and its application in protein subcellular localization prediction
Annual Meeting of the International Society for Computational Biology (ISCB), Michigan, June 25-29, 2005
[P1] Zhengdeng Lei and Yang Dai
A support vector machines approach to predict protein subcellular localization
Proteomics Symposium 2004, Chicago, April 17, 2004
Presentations
[2] International Conference on Computational Science, Emory University, Atlanta, 2005
[1] Sigma Xi Research Forum, Univeristy of Illinois at Chicago, Chicago, 2005
RESEARCH RESOURCE
Look up a linux/unix command: (e.g "chmod")
